Novel Urine Hepcidin Assay by Mass Spectrometry Running title: Urine hepcidin assay by SELDI-TOF-MS BRIEF REPORT Authors
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چکیده
BRIEF REPORT Authors Erwin Kemna, Harold Tjalsma, Coby Laarakkers, Elizabeta Nemeth, Hans Willems, Dorine Swinkels Department of Clinical Chemistry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. Corresponding author Erwin H.J.M. Kemna Department of Clinical Chemistry 564 Radboud University Nijmegen Medical Centre PO Box 9101 6500 HB Nijmegen The Netherlands Tel: +31 (0)24 – 3617676 Fax: +31 (0)24 – 3541743 E-mail: [email protected] Authors contribution Erwin Kemna: designed and performed research, analyzed data, and wrote the paper. Harold Tjalsma: analyzed data, and wrote the paper. Coby Laarakkers: designed research, and analyzed data. Elizabeta Nemeth: contributed analytical tools, analyzed data, and wrote the paper. Hans Willems: analyzed data. Dorine Swinkels: designed research, analyzed data, and wrote the paper.
منابع مشابه
Novel urine hepcidin assay by mass spectrometry.
The hepatic peptide hormone hepcidin is the central regulator of iron metabolism and mediator of anemia of inflammation. To date, only one specific immuno-dot assay to measure hepcidin in urine had been documented. Here we report an alternative approach for quantification of hepcidin in urine by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS). Peptid...
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